International Review of Ophthalmology

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Mechanism of immune privilege and immune responses in bacterial endophthalmitis

DUAN Yi-qin, LIN Ding   

  1. AIER School of Ophthalmology Central South University, Changsha AIER Eye Hospital, Changsha 410005, China
  • Received:2015-10-02 Online:2016-04-22 Published:2016-04-22
  • Contact: LIN Ding, Email: dlinoph@163.com

Abstract:

Bacterial endophthalmitis is an emergency in ophthalmology, which can cause serious vision loss. Though taken prompt and aggressive therapeutic and surgical intervention,devastating imparity in vision acuity may happen. Researches on bacterial endophthalmitis focus on analyzing the mechanisms of the inflammatory responses to infection and the molecular and cellular interactions between the pathogen and host. The latest advances in enucleating the mechanisms of bacterial endophthalmitis include immune privilege, innate immunity, complement system, fas ligand, cellular infiltration, cytokines and adhesion molecules.  (Int Rev Ophthalmol,  2016,  40:     132-135)